How to search information about a Domain

1. How to begin Searching Using Domain Name / PFAM ID


To search about the domain, just press the Domain Combination Tab. Enter the the domain name or the PFAM ID in the given text box and click Search.


P.S. If you were on Search by Taxon ID Page and the domain Name hyperlink redirected you here, good, You are at right place! The text box already contains the Domain Name you were searching for. A click on theSearch button will display the information in the table.

2. How to interpret the Results?


The search results a table with 3 fields in it namely Taxon ID, Uniprot ID and the Domain Information. The details are as follows:

  • Taxon ID
  • Uniprot ID
  • Domain Information : Structural domains which are self-stabilizing and fold independently of the rest of the protein chain. They may occur independently or as part of complex multidomain protein architectures. Protein domains can therefore be viewed as a ‘parts list’.
    • Name : Domain Name
    • PFAM ID : The unique identifier of protein families and domains in the Pfam database.
    • Start- End Region : The start and end value of this particular domain in the entire protein sequence.
    • E-Value : E-values are based on searching the family against KinG Database using HMMsearch.
    • % Similarity Match : How well database and query sequences match.


3. Where does the Uniprot ID hyperlink further take me?

As the user clicks on the Uniprot ID hyperlink, it takes the user to Uniprot ID page, Where the user is provided with the text box with the same name entry already filled. The User has to click on the Search button to view the information about the Uniprot ID.


4. Where does the PFAM ID hyperlink further take me?

As the user clicks on the PFAM ID hyperlink, it takes the user to an external link to PFAM Database page. The page gives the information about that particular family.